Search results for " acromegaly"

showing 5 items of 5 documents

Early Lung Function Abnormalities in Acromegaly.

2014

BACKGROUND: Acromegaly is an insidious disorder caused by a pituitary growth hormone (GH)-secreting adenoma resulting in high circulating levels of GH and insulin-like growth factor I (IGF-I). Respiratory disorders are common complications in acromegaly, and can severely impact on quality of life, eventually affecting mortality. OBJECTIVES: The present study aimed to explore structural and functional lung alterations of acromegalic subjects. METHODS: We enrolled 10 consecutive patients (M/F: 5/5) affected by acromegaly. In all patients, magnetic resonance imaging (MRI) revealed the presence of pituitary tumor. All patients underwent clinical, lung functional, biological, and radiological as…

AdultLung DiseasesMalePulmonary and Respiratory MedicinePathologymedicine.medical_specialtyTime FactorsAdenomaVital CapacitySettore MED/10 - Malattie Dell'Apparato RespiratorioGastroenterologyspirometry dyspnea acromegalySettore MED/13 - EndocrinologiaPredictive Value of TestsDLCOForced Expiratory VolumeDiffusing capacityInternal medicineAcromegalymedicineHumansLung volumesRespiratory systemLungAgedLungbusiness.industryPituitary tumorsMiddle Agedrespiratory systemmedicine.diseaseMagnetic Resonance Imagingrespiratory tract diseasesRadiographyEarly Diagnosismedicine.anatomical_structureCase-Control StudiesPulmonary Diffusing CapacityFemaleGrowth Hormone-Secreting Pituitary AdenomaLung Volume Measurementsbusiness
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Impact of COVID-19 Pandemic on Disease Control Status and Quality of Life of Patients with Acromegaly.

2022

Background and Objectives: Despite the best efforts of healthcare workers and the deployment of alternative healthcare delivery solutions through telemedicine, the pandemic has disrupted standard care for patients with chronic conditions. The long-lasting pandemic has also had a profound impact on the quality of life (QoL) of the majority of patients with chronic illnesses. The management of rare diseases has been particularly challenging. We aimed to evaluate the impacts that the long-lasting pandemic had on the disease control status and QoL in patients with acromegaly. Materials and Methods: Our prospective study included 34 patients from a national referral centre. The baseline SAGIT an…

SARS-CoV-2Surveys and QuestionnairesAcroQoL COVID-19 pandemic SAGIT instrument acromegaly disease control status public health measuresAcromegalyCommunicable Disease ControlQuality of LifeHumansRNA ViralCOVID-19General MedicineProspective Studiesacromegaly; disease control status; SAGIT instrument; AcroQoL; COVID-19 pandemic; public health measuresPandemicsMedicina (Kaunas, Lithuania)
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Assessment of the awareness and management of sleep apnea syndrome in acromegaly. The COM.E.TA (Comorbidities Evaluation and Treatment in Acromegaly)…

2011

In 2007 the Italian COM.E.T.A. (COMorbidities Evaluation and Treatment in Acromegaly) study group started to assess the application in a clinical setting of the Versailles criteria for management of acromegaly complications by a first questionnaire focusing on cardiovascular co-morbidities. A further questionnaire on sleep apnea syndrome (SAS) was delivered by the COM.E.T.A. study group to 107 endocrine centers in Italy. The results of our survey suggest that SAS is a well-known comorbidity even if its estimated prevalence is lower than in the literature. Polysomnography is the preferred tool for diagnosis. Control of SAS is considered relevant both for quality of life and co-morbidities. C…

MalePediatricsmedicine.medical_specialtymedicine.medical_treatmentEndocrinology Diabetes and MetabolismPolysomnographyPolysomnographyComorbiditysomatostatin analogs; acromegaly; sleep apnea syndromeSettore MED/13 - EndocrinologiaSomatostatin analogEndocrinologySleep Apnea SyndromesQuality of lifeAcromegaly; Sleep apnea syndrome; Somatostatin analogs;PhysiciansSurveys and QuestionnairesAcromegalymedicinePrevalenceHumansContinuous positive airway pressuremedicine.diagnostic_testbusiness.industrySleep apneaAwarenessFocus Groupssleep apneamedicine.diseaseComorbidityAcromegaly; Sleep apnea syndrome; Somatostatin analogsAcromegaly; Sleep ApneaSleep apnea syndromeItalySomatostatin analogsAcromegalyPhysical therapyCOM.E.TA.FemaleClinical Competencebusiness
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Central Corneal Thickness in patients with acromegaly

2011

Introduction Acromegaly is hormonal disorder caused by excessive growth hormone (GH) by the pituitary gland, this results in anatomical changes in many organs and also in the eye and specially in cornea. Objective To perform a connection between the disease activity and the corneal changes Matériels et Méthodes In 28 patients with acromegaly and in 22 voluntary healthy the central corneal thickness (CCT) was measured by pachymeter. And the patients were divided in 2 groups: the first (“group A”) contains 13 cases with not controlled acromegaly; and the other one (“group B”) is related to 15 patients with controlled acromegaly Résultats Patients with acromegaly have a central corneal thickne…

Settore MED/30 - Malattie Apparato Visivocorneal thickness acromegaly GH
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The role of elevated growth hormone on the increased atherosclerosis in patients with acromegaly.

2012

medicine.medical_specialtybusiness.industryHuman Growth HormoneMEDLINEGrowth Hormone Atherosclerosis AcromegalyBioinformaticsmedicine.diseaseGrowth hormoneAtherosclerosisText miningEndocrinologyRisk FactorsInternal medicineAcromegalyAcromegalymedicineHumansIn patientInsulin ResistanceInsulin-Like Growth Factor ICardiology and Cardiovascular MedicinebusinessAngiology
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